Corticotropin-releasing hormone receptors.

نویسندگان

  • E W Hillhouse
  • H Randeva
  • G Ladds
  • D Grammatopoulos
چکیده

Corticotropin-releasing hormone (CRH) and related peptides (urocortins, sauvagine, urotensin) play a central role in the co-ordination of autonomic, behavioural, cardiovascular, immune and endocrine responses to stressful stimuli. Their actions are mediated through activation of two types of G-protein-coupled receptors encoded by separate genes. In this review we focus on the diverse structural and functional characteristics of the family of CRH-like peptides and their receptors.

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عنوان ژورنال:
  • Biochemical Society transactions

دوره 30 4  شماره 

صفحات  -

تاریخ انتشار 2002